CHEM 225 - Survey of Organic and Biochemistry 4 Credit: (3 lecture, 2 lab, 0 clinical) 5 Contact Hours: [CHEM 105 or CHEM 220 ]
This class is designed to emphasize selected topics in general chemistry and introduce topics in organic and biological chemistry. Emphasis is on bonding, functional groups, physical properties, and general reactivity of organic molecules. These concepts are then applied to the study of biomolecules and biological pathways.
Semesters Offered: Spring Semester
Course Goals/ Objectives/ Competencies:
Goal 1: Demonstrate a working knowledge of common organic compounds based on their functional group.
1. Identify the structures of alkanes, alkenes, and cycloalkenes.
2. Name alkanes, alkenes, and cycloalkenes using IUPAC and common nomenclature.
3. Describe the physical properties of alkanes, alkenes, and cycloalkenes.
4. Describe the chemical properties of alkanes, alkenes, and cycloalkenes.
5. Identify the structural features of alcohols, ethers, and thiols.
6. Name alcohols, ethers, and thiols using nomenclature rules.
7. Describe the physical properties of alcohols, ethers, and thiols.
8. Describe the chemical properties of alcohols, ethers, and thiols.
9. Identify commonly encountered alcohols.
10. Identify the structures, features, and common reactions of aldehydes and ketones.
11. Apply proper nomenclature rules to aldehydes and ketones.
12. Describe the chemical properties of aldehydes and ketones.
13. Identify commonly encountered aldehydes and ketones.
14. Identify carboxylic acids, anhydrides, and esters.
15. Identify the structural features of amines and amides.
16. Name amines and amide molecules using nomenclature rules.
17. Describe the chemical properties and preparation of amines and amides.
Goal 2: Apply properties of organic compounds to the macromolecules of life.
1. Describe the occurrence and function of carbohydrates.
2. Explain the chirality of carbohydrates.
3. Describe Fischer Projections.
4. Name the properties of enantiomers.
5. Classify monosaccharides and identify their reactions.
6. Identify polysaccharides, glycolipids, and glycoproteins.
7. Identify fatty acids, waxes, phosphoacylgycerols, steroids, fats, oils, and eicosanoids.
8. Describe the reactions of triglycerides.
9. Explain the transport of lipids across cell membranes.
10. Name the amino acids.
11. Name properties of acids and bases in organic molecules.
12. Describe peptide formation.
13. Describe protein structure, hydrolysis, and denaturation.
14. Identify glycoproteins and lipoproteins.
15. Identify the types and structures of nucleic acids.
16. Explain nucleic acid involvement in protein synthesis.
17. Explain synthesis and the role of RNA to genetic code.
18. Describe translation and mutation of proteins.
19. Describe the characteristics, structure, and formation of enzymes.
20. Name enzymes using nomenclature.
21. Identify factors that affect enzyme activity.
22. Name medical uses of enzymes.
Goal 3: Explain the relationships that exist amongst an organism’s biochemical pathways for obtaining energy.
1. Describe digestion.
2. Identify reaction end-products in energy production.
3. Identify relationships between metabolic pathways (glycolysis and TCA cycle).
4. Describe reactions of the electron transport chain.
5. Explain how ATP plays a central role in the production and use of cellular energy.
Goal 4: Use laboratory techniques and equipment appropriately to analyze outcomes.
1. Perform various physical separation techniques in the laboratory setting. These include gel electrophoresis, extraction, crystallization, centrifugation, and thin-layer chromatography.
2. Utilize proper equipment in the laboratory setting. These include melting point apparatus, gas chromatograph, Fourier Transform Infrared Spectrometer (FTIR), and various organic glassware.
3. Work safely in the laboratory setting.
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